南京科佰生物科技有限公司官方网站欢迎您的光临！
免费咨询热线： 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
KRAS p.Q61K Reference Standard
|
CBP10302
|
|
| Format | Genomic DNA |
| Description | KRAS Q61K is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). Q61K has not been characterized, but can be predicted to confer a loss of function on Kras protein based on the effects of HRAS Q61K, which results in decreased Hras GTPase activity and leads to transformation of cells in culture (PMID: 3510078). |
| Technical Data | |
| DNA Change | c.181C>A |
| AA Change | p.Q61K |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 93.78% |
| Transcript | ENST00000311936 |
| Cosmic ID | COSM549 |
| Chr position(GRCh37) | chr12:25380277 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
扫一扫，关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 南京科佰生物科技有限公司版权所有 苏ICP备13038923号