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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
PIK3CA p.H1047L Reference Standard
CBP10320
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Format | Genomic DNA |
Description | PIK3CA H1047L is a hotspot mutation that lies within the PI3K/PI4K domain of the Pik3ca protein (UniProt.org). H1047L confers a gain of function on the Pik3ca protein as indicated by increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and transformation in cell culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.3140A>T |
AA Change | p.H1047L |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | NM_006218.1 |
Cosmic ID | COSM776 |
Chr position(GRCh37) | chr3:178952085 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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