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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
PIK3CA p.E542K Reference Standard
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CBP10324
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| Format | Genomic DNA |
| Description | PIK3CA E542K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E542K results in increased phosphorylation of Akt, growth factor-independent cell survival, and is transforming in cell culture (PMID: 16533766, PMID: 26627007, PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1624G>A |
| AA Change | p.E542K |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_006218.1 |
| Cosmic ID | COSM760 |
| Chr position(GRCh37) | chr3:178936082 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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