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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AI-Edigene® EGFR p.C797S Reference Standard Plus
CBP10342
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Format | Genomic DNA |
Description | EGFR C797S lies within the ATP-binding pocket in the protein kinase domain of the Egfr protein (PMID: 25964297). C797S has been demonstrated to confer resistance to third-generation EGFR inhibitors (PMID: 25964297, PMID: 25948633, PMID: 29410323), but has not been biochemically characterized and therefore, its effect on Egfr protein function is unknown (PubMed, Jun 2018). |
Technical Data | |
DNA Change: | c.2390G>C |
AA Change | p.C797S |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000275493 |
Cosmic ID | COSM5945664 |
Chr position(GRCh37) | chr7:55249092 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |

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