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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AI-Edigene® BRAF p.V600G Reference Standard Plus
CBP10427
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Format | Genomic DNA |
Description | BRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040). |
Technical Data | |
DNA Change | c.1799T>G |
AA Change | p.V600G |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000288602 |
Cosmic ID | COSM6137 |
Chr position(GRCh37) | chr7:140453136 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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