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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AI-Edigene® NRAS p.Q61R Reference Standard Plus
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CBP10471
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| Format | Genomic DNA |
| Description | NRAS Q61R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61R results in a loss of Nras GTPase function as indicated by increased GTP-bound Nras, which leads to activation of Mapk signaling in culture (PMID: 16818621). |
| Technical Data | |
| DNA Change: | c.182A>G |
| AA Change | p.Q61R |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000369535 |
| Cosmic ID | COSM584 |
| Chr position(GRCh37) | chr1:115256529 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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