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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
TP53 p.V218del Reference Standard
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CBP10442
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| Gene | TP53 |
| Description | TP53 V218del results in the deletion of one amino acid within the DNA-binding domain of the Tp53 protein (PMID: 21760703). V218del has been identified in sequencing studies (PMID: 30212483, PMID: 26454445, PMID: 25356985), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, May 2019). |
| Technical Data | |
| DNA Change | c.652_654delGTG |
| AA Change | p.V218del |
| Mutation type | In_Frame_Del |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000420246.2 |
| Cosmic ID | COSM6496 |
| Chr position(GRCh37) | chr17:7578201_7578203 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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