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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
FGFR2 p.N550K Reference Standard
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CBP10475
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| Format | Genomic DNA |
| Description | FGFR2 N550K (corresponds to N549K in the canonical isoform) lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). N550K results in increased Fgfr2 kinase activity and enhanced cell proliferation in the presence of ligand in culture (PMID: 23908597). |
| Technical Data | |
| DNA Change: | c.1650T>G |
| AA Change | p.N550K |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Copy Number | 3 |
| Ploidy | 2.17 |
| Allelic Frequency | 100.00% |
| Transcript | ENST00000457416.6 |
| Cosmic ID | COSM36902 |
| Chr position(GRCh37) | chr10:123258034 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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