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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
MAP2K1 p.Q56P Reference Standard
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CBP10496
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| Format | Genomic DNA |
| Description | MAP2K1 Q56P does not lie within any known functional domains of the Map2k1 protein (UniProt.org). Q56P confers a gain of function to the Map2k1 protein as indicated by increased kinase activity and the ability to transform cultured cells (PMID: 22327936, PMID: 7651428) and also demonstrates resistance to some Mek and Braf inhibitors (PMID: 29753091). |
| Technical Data | |
| DNA Change | c.167A>C |
| AA Change | p.Q56P |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000307102.9 |
| Cosmic ID | COSM1235481 |
| Chr position(GRCh37) | chr15:66727451 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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