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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
NRAS p.G13V Reference Standard
CBP10515
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Format | Genomic DNA |
Description | NRAS G13V is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13V has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G13V, which results in a loss of response to GTPase-activating proteins, leading to increased GTP-bound Hras in culture (PMID: 24224811). |
Technical Data | |
DNA Change | c.38G>T |
AA Change | p.G13V |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | ENST00000369535.4 |
Cosmic ID | COSM574 |
Chr position(GRCh37) | chr1:115258744 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | ![]() |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |

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