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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CHEK1 p.L355* Reference Standard
CBP10540 | |
Format | Genomic DNA |
Description | CHEK1, checkpoint kinase 1, is a serine/threonine kinase activated in response to DNA damage that is responsible for mediating checkpoint signaling from ATM and ATR (PMID: 23613359, PMID: 12781359). Overexpression of Chek1 has been observed in several tumor types, including gastric cancer, small cell lung cancer, T-cell leukemia (PMID: 25132270, PMID: 26867682, PMID: 28490518), and breast cancer (PMID: 31933717). |
Technical Data | |
DNA Change: | c.1064delT |
AA Change | p.L355* |
Mutation type | Frame_Shift_Del |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | NM_001274.5 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr11:125514126 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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