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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CEBPA p.T337M Reference Standard
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CBP10546
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| Format | Genomic DNA |
| Description | CEBPA, CCAAT enhancer binding protein alpha, is a transcription factor that regulates the expression of genes involved in cell differentiation (PMID: 26601784). Inactivation of CEBPA is associated with the pathogenesis of leukemia, including biallelic CEBPA-mutant AML (PMID: 32086816), and dysregulation of CEBPA has been identified in various solid tumors (PMID: 28720765, PMID: 28504718). |
| Technical Data | |
| DNA Change | c.1010C>T |
| AA Change | p.T337M |
| Mutation type | Missense_Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | NM_004364.5 |
| Cosmic ID | COSM2751513 |
| Chr position(GRCh37) | chr19:33792311 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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