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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
EZR-ROS1/BaF3
| CBP73324 | |||
| I. Introduction | |||
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Cell Line Name： |
EZR-ROS1/BaF3 |
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Host Cell: |
Ba/F3 |
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| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | ||
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
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| II.Background | |||
| EZR, ezrin, is a member of the ERM family that links the cytoplasm to the actin cytoskeleton and regulates polarization and migration in leukocytes and macrophages. EZR plays a role in metastasis in a number of cancer types although decreased Ezr expression has been associated with decreased survival in clear cell renal carcinoma and an EZR-ROS1 fusion has been identified in lung cancer. | |||
| III. Representative Data | |||
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1.Sanger of EZR-ROS1/BaF3
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2. Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 EZR-ROS1 (C5). |
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