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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
KRAS p.G13C Reference Standard
CBP10299#
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Format | Genomic DNA |
Description | KRAS G13C is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G13C results in decreased Kras GTPase activity, as indicated by increased Ras-GTP, and leads to activation of downstream signaling in cell culture (PMID: 25705018, PMID: 21079152). |
Technical Data | |
DNA Change | c.37G>T |
AA Change | p.G13C |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000311936 |
Cosmic ID | COSM527 |
Chr position(GRCh37) | chr12:25398282 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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