|CXCR1 (C-X-C Motif Chemokine Receptor 1) is a Protein Coding gene.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.|
|Stability:||20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||F12K+10%FBS+5ug/ml puromycin|
|Storage:||Liquid nitrogen immediately upon delivery|
Functional assay for CXR1 receptor
|Ⅲ. Description of Host Cell Line|
|Ⅳ. Representative Data|
Figure 1. Recombinant CXCR1/CHO constitutively expressing CXCR1.
Figure 2. IL-8 efffect on CHO-CXCR1 clone 6.