|Calcitonin receptor‐like (CALCRL) is a G-protein coupled neuropeptide receptor involved in various biological processes such as proliferation, apoptosis, and inflammation.|
|Stability:||20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||DMEM+10%FBS+2ug/ml puromycin+5ug/ml blastcidin|
|Storage:||Liquid nitrogen immediately upon delivery|
|Ⅲ. Description of Host Cell Line|
|Ⅳ. Representative Data|
Figure 1. Dose Response of Agonists in Human CALCRL/RAMP1 CRE Luc Reporter HEK293 Cells (C1).
Figure 2. Inhibtion of αCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.
Figure 3. Inhibition of βCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.