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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CALCRL/RAMP1/CRE-Luc/HEK293
CBP71361 | |
I. Background | |
Calcitonin receptor‐like (CALCRL) is a G-protein coupled neuropeptide receptor involved in various biological processes such as proliferation, apoptosis, and inflammation. | |
II. Introduction | |
Host Cell: |
HEK293 |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+2ug/ml puromycin+5ug/ml blastcidin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Transducer: | Gs |
Ⅲ. Description of Host Cell Line | |
Organism: | Human |
Tissue: | kidney |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. Dose Response of Agonists in Human CALCRL/RAMP1 CRE Luc Reporter HEK293 Cells (C1). Figure 2. Inhibtion of αCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.
Figure 3. Inhibition of βCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells. |

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