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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
CYP2D6*2 Reference Standard
CBPA0045 | |
Format | Genomic DNA |
Description | CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients. |
Technical Data | |
Gene | CYP2D6*2 |
Mutation Type 1 | AA Change: p.R296C |
DNA Change: NM_000106.6:c.886C>T | |
Chr position (GRCh38): NC_000022.11:g.42127941G>A | |
Mutation Type 2 | AA Change: p.S486T |
DNA Change: NM_000106.6:c.1457G>C | |
Chr position (GRCh38):NC_000022.11:g.42126611C>G | |
Allelic Frequency | 50% |
Zygosity | Heterozygous |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing |
Figure 1. CYP2D6*2 Reference Standard p.R296C Figure 2. CYP2D6*2 Reference Standard p.S486T |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |

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