科研细胞

科研细胞

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药靶细胞

药靶细胞

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标准品

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NGS靶向捕获探针

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1000

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0.0

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1000

产品编号

CBP74175

货号:

CBP74175

品牌:

Cobioer

规格:

T-25 Flask

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CBP74175
I. Background
Interleukin-22 (IL-22) is protein that in humans is encoded by the IL22 gene.IL-22 primarily targets non-hematopoietic epithelial and stromal cells where it can promote proliferation and play a role in tissue regeneration. In addition, IL-22 regulates host defense at barrier surfaces. However, IL-22 has also been linked to several conditions involving inflammatory tissue pathology.

II.Introduction
Expressed gene:	IL22R
Stability:	32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):	Interleukin-22、IL-TIF、ILTIF、ZCYTO18
Freeze Medium:	90% FBS+10%DMSO
Culture Medium:	DMEM+10%FBS+2ug/ml puromycin+200ug/ml hrgromycin+5ug/ml blasticidin
Mycoplasma Testing:	Negative
Storage:	Liquid nitrogen
Application(s):	Functional(Report Gene) Assay

III. Representative Data
Figure 1. Recombinant IL22 Effector Reporter Cell constitutively expressing IL22R.
Figure 2. Recombinant IL22 Effector Reporter Cell constitutively expressing IL10RB.
Figure 3.Dose Response of Recombinant Human IL-22 in Human IL-22 Effector Reporter Cells(C8).
Figure 4.Inhibition of IL-22-induced Reporter Activity By IL-22 Neutralization Ab in IL-22 Effector Reporter Cells(C8).