南京科佰生物科技有限公司官方网站欢迎您的光临！
免费咨询热线： 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
MLH1 p.L155Sfs*17 Reference Standard
|
CBP10589
|
|
| Format | Genomic DNA |
| Description | MLH1, mutL homolog 1, is a tumor suppressor that dimerizes with Pms2 to form a component of the DNA mismatch repair (MMR) system, and is associated with microsatellite instability (MSI) and genomic stability. MLH1 promoter hypermethylation, resulting in Mlh1 deficiency, is frequently associated with sporadic colorectal, gastric, and esophageal cancers, and germline MLH1 mutations are associated with Lynch (Hereditary Nonpolyposis Colorectal Cancer) syndrome. |
| Technical Data | |
| DNA Change | c.462_463insT |
| AA Change | p.L155Sfs*17 |
| Mutation type | Frame_Shift_Ins |
| Zygosity | N/A |
| Allelic Frequency | N/A |
| Transcript | NM_000249.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr3-37050314--T |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
扫一扫，关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 南京科佰生物科技有限公司版权所有 苏ICP备13038923号