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科研细胞
药靶细胞
标准品
NGS靶向捕获探针
AI-Edigene® EGFR VIII (E2-E7del) Translocation
CBP20203D#
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Format | DNA |
Description | EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth. EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancerand colorectal cancer, and the EGFRvIII variant is commonly found in glioblastoma. |
Technical Data | |
Left Gene | EGFR(E2) |
Left Breakpoint | chr7:55206313:+ |
Right Gene | EGFR(E7) |
Right Breakpoint | ch2:55223325:+ |
%AF | 50% |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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