南京科佰生物科技有限公司官方网站欢迎您的光临!
免费咨询热线: 4008-750-250
科研细胞
药靶细胞
标准品
NGS靶向捕获探针
GLP1R/CRE-Luc/BHK
CBP71405 | |
I. Background | |
GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently, GLP1R has been suggested as a potential target for the treatment of diabetes. GLP1R is also expressed in the brain where it is involved in the control of appetite. Furthermore, mice which over express GLP1R display improved memory and learning. |
|
II. Introduction | |
Host Cell: | BHK |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | GLP1R |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | MEM+10% FBS+1% Non Essential Amino Acids (NEAA)+1 mM sodium pyruvate+2ug/ml puromycin+800ug/ml hygromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): |
Functional assay for GLP1R receptor |
Transducer: | Gs |
Ⅲ. Description of Host Cell Line | |
Organism: | Mesocricetus auratus, hamster, Syrian golden |
Tissue: | kidney |
Disease: | Normal |
Morphology: | fibroblast |
Growth Properties: | Adherent |
Ⅳ.Representative Data | |
Figure 1.GLP1R/CRE Reporter -BHK Recombinant Cell Line (C22). |
扫一扫,关注我们公众号
Copyright ©2021 www.cobioer.com All Rights Reserved. 南京科佰生物科技有限公司版权所有 苏ICP备13038923号