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DKK-1 Effector Reporter Cell

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DKK-1 Effector Reporter Cell

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产品编号
CBP74200
货号:
CBP74200
品牌:
Cobioer
规格:
T-25 Flask
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CBP74200
I. Background
DKK1, dickkopf WNT signaling pathway inhibitor 1, is a glycoprotein that acts to inhibit canonical Wnt signaling, and may play a role in cellular differentiation, proliferation, and apoptosis. Increased expression of Dkk1 is associated with metastasis in hilar cholangiocarcinoma, and both low and high levels of Dkk1 expression have been demonstrated in various tumor types, including lung cancer and hepatocellular carcinoma, respectively.
 
II.Introduction
Expressed gene: DKK-1
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10%DMSO
Culture Medium: DMEM+10%FBS+2ug/ml puromycin+100ug/ml hygromycin
Mycoplasma Testing: Negative
Storage: Liquid nitrogen
Application(s): Functional(Report Gene) Assay
 
III. Representative Data

Figure 1.Dose Responese of DKK-1 Neutralization Ab to Rescue the Inhibition of Recombinant hWnt-3a Induced Reporter Activity by DKK-1 in DKK-1 Effector Reporter Cells (C11).

 
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  • DKK-1 Effector Reporter Cell CBP74200说明书.pdf

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    2024-04-02
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