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AI-Edigene® POLE p.S297F Reference Standard Plus

科研细胞

科研细胞

药靶细胞

药靶细胞

标准品

标准品

NGS靶向捕获探针

NGS靶向捕获探针
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AI-Edigene® POLE p.S297F Reference Standard Plus

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产品编号
CBP10682
货号:
CBP10682
品牌:
Cobioer
规格:
1ug
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 CBP10682
Format Genomic DNA
Description POLE, DNA polymerase epsilon catalytic subunit, mediates proofreading activity during DNA repair and replication and plays a role in genomic stability. Somatic mutations in POLE have been identified in colorectal cancer, frequently in endometrial cancer, and are often associated with high tumor mutational burden, but are less likely to be associated with DNA mismatch repair (MMR) deficiency.
   
Technical Data 
DNA Change c.890C>T
AA Change p.S297F
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50%
Transcript NM_006231.4
Cosmic ID COSM937330
Chr position(GRCh38) chr12-132676565-G-A
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 4℃
Expiry 36 months from the date of manufacture
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