Dectin1b Effector Reporter Cell
CBP74550
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| I. Background | |
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Dectin1b 是 Dectin-1 受体的一个亚型（Isoform B），属于C型凝集素受体家族。它主要表达于髓系免疫细胞表面，作为模式识别受体特异性识别真菌细胞壁成分β-葡聚糖，在启动抗真菌免疫应答中发挥核心作用。 |
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| II. Description | |
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Dectin1b Effector Reporter Cell 报告基因药靶模型很好的模拟了体内 Dectin1b 的信号转导过程。 |
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| III. Introduction | |
| Expressed gene: | Dectin1b |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | MEM+10%FBS + 1% NEAA+ 1mM NaP+ 1 μg/ml Puromycin+ 100 μg/ml Hygromycin B+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
IV. Representative Data Figure 1. Dose Response of Ligands in Dectin-1b Effector Reporter Cell(Adherent, C35). |
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