HCN4 HEK293
CBP75107
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产品描述
产品数据库
| I. Background | |
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CN4(超极化激活环核苷酸门控阳离子通道 4)是产生心脏自主起搏电流(If)的核心分子,高度表达于窦房结,决定心率快慢。该通道能被超极化电压激活,并由 cAMP 直接调控,介导钠/钾内向电流,驱动舒张期去极化。HCN4 突变可致窦性心动过缓、病态窦房结综合征等心律失常。 |
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| II. Description | |
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HCN4 HEK293 细胞,在 HEK293 细胞的基础上,稳定表达 HCN4。 |
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| III. Introduction | |
| Expressed gene: | HCN4 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+ 10% FBS+ 2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| IV. Representative Data | |
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