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pCBRG-IRF1 RE

CBV20034

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Introduction
Description: pIRF1 RE-Luc is designed for monitoring the induction of Interferon Regulatory Factor 1.Interferon regulatory factor 1 was the first member of the interferon regulatory transcription factor (IRF) family identified. Initially described as a transcription factor able to activate expression of the cytokine Interferon beta,IRF-1 was subsequently shown to function as a transcriptional activator or repressor of a variety of target genes. IRF-1 regulates expression of target genes by binding to an interferon stimulated response element (ISRE) in their promoters. The IRF-1 protein binds to the ISRE via an N-terminal helix-turn-helix DNA binding domain,which is highly conserved among all IRF proteins.
Plasmid profile:
Unit Size: 1-4μg
Pathway (Activitor): IRF1
Pathway profile:
Full Name: Interferon Regulatory Factor 1
Cis response element: IRF1 RE
Shelf Life: One year from date of receipt under proper storage conditions.
Storage: -20°C
Mode of transportation: Ice bag transport
Matters needing attention: For your health, please wear lab clothes and disposable gloves.

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