NPR1 CHO
CBP74566
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| I. Background | |
| NPR1(利钠肽受体1,又称GC-A)是一种鸟苷酸环化酶偶联受体,主要在心血管系统中表达。 作为心房利钠肽(ANP)和脑利钠肽(BNP)的主要受体,NPR1被激活后能催化生成cGMP,从而扩张血管、降低血压、促进排钠利尿。 NPR1在维持心血管稳态中起核心作用,其功能障碍与高血压、心肌梗死等疾病密切相关。 | |
| II. Description | |
| NPR1 CHO细胞,在 CHO-K1 细胞的基础上,稳定表达 NPR1 。 | |
| III. Introduction | |
| Expressed gene: | NPR1 |
| Host Cell: | CHO-K1 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
![]() Figure 1. Recombinant NPR1 CHO constitutively expressing NPR1. |
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