IL11RA HEK293
CBP74571
询 价
索取Protocol
产品描述
产品数据库
| I. Background | |
| IL11RA(白介素-11受体α亚基)是由3590号基因编码的I型细胞因子受体。它是IL-11信号传导的关键受体,需要与gp130分子共同形成复合物才能向细胞内传递信号。 IL11RA在颅面部骨骼和牙齿的正常发育中发挥重要作用,其功能缺失可导致颅缝早闭及牙齿发育异常综合征(CRSDA)。在疾病方面,IL11RA参与心脏纤维化、胰腺炎及肿瘤耐药等过程,近年已成为骨肉瘤CAR-T治疗的潜在靶点。 | |
| II. Description | |
| IL11RA HEK293细胞,在 HEK293细胞的基础上,稳定表达 IL11RA 。 | |
| III. Introduction | |
| Expressed gene: | IL11RA |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
![]() Figure 1. Recombinant IL11RA HEK293 constitutively expressing IL11RA. |
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