PTEN p.T319* Reference Standard
CBP10759
询 价
索取COA
产品描述
产品数据库
| Introduction | |
| Format | Genomic DNA |
| Description |
PTEN p.T319* 是一个在PTEN基因中发生的无义突变，导致其编码的蛋白质在第319位苏氨酸（T）处提前终止，产生一个截短且功能丧失的蛋白，从而破坏其关键的抑癌功能，该突变与多种癌症的发病风险增高相关。
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| Technical Data | |
| DNA Change | c.955_958del |
| AA Change | p.T319* |
| Mutation type | Deletion |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_000314.8 |
| Cosmic ID | COSM4894 |
| Chr position(GRCh37) | chr10:89720804_89720807 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
