Mouse CTR COS7
CBP71641
询 价
索取protocol
产品描述
产品数据库
| I. Background | |
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小鼠CTR(降钙素受体,Calcitonin Receptor)是由Calcr基因编码的B类G蛋白偶联受体,在不仅是降钙素的内源性受体,还能与RAMPs蛋白家族成员结合,形成对胰淀素(amylin)和CGRP等配体具有不同亲和力的多种受体复合物。 小鼠CTR的药理学特性与人类受体存在显著差异,其对不同配体的选择性较低,表现为一种“广谱”特性。 |
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| II. Description | |
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Mouse CTR COS7 细胞,在 COS7 细胞的基础上,稳定表达Mouse CTR。 |
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| III. Introduction | |
| Expressed gene: | Mouse CTR |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM + 10%FBS + 2μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for Mouse CTR |
| Transducer: | Gs |
IV. Representative Data![]() Figure 1. HTRF cAMP Assay with Mouse CTR COS7(C78). |
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