STEAP1 HEK293
CBP74584
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| I. Background | |
| STEAP1（Six Transmembrane Epithelial Antigen of the Prostate 1，前列腺癌六次跨膜上皮抗原1）定位于人染色体 7q21.13，编码细胞膜上的六次跨膜蛋白，属 STEAP 金属氧化还原酶家族。它主要表达于前列腺、膀胱等组织及多种肿瘤细胞（前列腺癌、膀胱癌、尤文肉瘤等），定位于质膜及细胞间连接处，具铁/铜金属离子还原活性，参与金属离子转运与细胞间通讯，是肿瘤 ADC（抗体偶联药物）热门靶点。 | |
| II. Description | |
| STEAP1 HEK293细胞，在 HEK293细胞的基础上，稳定表达 STEAP1 。 | |
| III. Introduction | |
| Expressed gene: | STEAP1 |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant STEAP1 HEK293 constitutively expressing STEAP1. |
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