DLD1-BRCA2-/-
CBP75005
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| I. Introduction | |
| Host Cell: | DLD1 |
| Expressed gene: | BRCA2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS |
| Storage: | Liquid nitrogen |
| Growth Mode: | Adherent |
| II.Background | |
| Breast cancer susceptibility gene (BRCA) is an important tumor suppressor gene, including BRCA1 and BRCA2. The BRCA1/2 gene is an important biomarker for assessing the risk of breast cancer, ovarian cancer and other related cancers, and it is also a biomarker that affects the selection of individualized treatment options for patients. | |
| III. Representative Data | |
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1.WB of DLD1-BRCA2-/-
Figure 1. DLD1-BRCA2-KO cell WB data |
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2. Sanger of DLD1-BRCA2-/-
Figure 2. BRCA2 p.Y42 c.124_125del |
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| 3. Anti-proliferation assay | |
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Figure 3. CTG Proliferation Assay of DLD-1 BRCA2 KO Cells. |
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