c-Kit D820Y/BaF3
CBP73236
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| I. Background | |
| KIT D820Y lies within the protein kinase domain of the Kit protein (UniProt.org). D820Yresuts in constitutive phosphorylation of Kit and is transforming in cell culture, and has also been identified as a secondary mutation associated with imatinib-resistance. | |
| II. Introduction | |
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Cell Line Name： |
c-Kit D820Y/BaF3 |
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Host Cell: |
BA/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| III. Representative Data | |
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1. WB of c-Kit D820Y/BaF3
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2.Sanger of c-Kit D820Y/BaF3
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3. Anti-proliferation assay
Figure 3. CTG Proliferation Assay of BaF3 c-KIT D820Y (C1). |
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